European Society of Medicine - list of abstracts for conferences and other related information

Maha Abdelgaber Abdellah Aly, Lecturer of Audiovestibular medicine, Faculty of Medicine, Assiut university, Egypt. Nonsyndromic hearing loss is an extremely heterogeneous disorder. Thus, clinical diagnostics is challenging, in particular due to differences in the etiology of hearing loss between populations. With this study, we wanted to elucidate the genetic basis of hearing loss in 61 consanguineous Egyptian families. In 25 families, linkage analysis was used as a prescreening to identify regions for targeted sequencing of candidate genes. Initially, the coding regions of 12 and later of 94 genes associated with hearing loss were enriched and subjected to massively parallel sequencing (MPS) with diagnostic yields of 36% and 75%, respectively. Causative variants were identified in 48 families (79%). They were found in 23 different genes with the majority being located in MYO15A (15.3%), SLC26A4 (9.7%), GJB2 (8.3%), and MYO7A (6.4%). As many as 32 variants were novel ones at the time ...

Libia Vega, Centre for Research and Advances Studies of the National Polytechnic Institute "Many classical antineoplastic agents induce myelosuppression, leukopenia and immunosuppression as secondary effects in patients reducing their quality of life and generating an increase in their incidence of infections. The development of anticancer agents that simultaneously provoke antitumor immune response represents an important therapeutic advance. The administration of 6-pentadecyl salicylic acid (6SA) contributes to the antitumor immunity as it pre-activates T lymphocytes and natural killer cells, and it induces macrophage polarisation that could contribute to the antitumoral respond against 4T1 stage IV-breast cancer cells in Balb/c female mice. 6SA increases the proportion of immune cells in blood, lymph nodes, bone marrow, and of tumor-infiltrated natural killer cells and cytotoxic T lymphocytes. It also increases the secretion of interleukin (IL)-2, IL-12, Granulocyte/Monocyte ...

Shu Yun Heng, Singapore General Hospital "The acceptable incidence of thrombophlebitis following intravenous cannulation is 5%, as recommended by the Intravenous Nurses Society guidelines, but publications have reported startling figures of 20% to 80%. Given the frequency of intravenous lines, this presents a potential clinical problem. Thrombophlebitis can progress despite antibiotics to become a challenging clinical problem requiring surgical intervention. We aimed to determine the predisposing patient, catheter, and health care-related factors of peripheral vein thrombophlebitis in the upper extremity. We reviewed our experience of surgical intervention with analysis of the indications for intervention, description of the surgical procedures and outcomes. Qualitative syntheses revealed that patient-related factors that confer a higher risk included intercurrent illness, immunocompromised state, comorbidities such as diabetes mellitus, malignancy, previous thrombophlebitis, bu...

Philip Chen, University of Texas Health at San Antonio Endoscopic sinus surgery is a commonly performed surgery, but learning to operate in a confined space with variable anatomy in a 2-dimensional view can be challenging. Simulation is being increasingly used to teach various types of surgery including endoscopic sinus surgery. Goals of simulation include faster learning in a safe environment. However, creation of valid models is challenging and an area for growth. For more details please visit our website https://esmed.org/ and our YouTube channel below https://www.youtube.com/channel/UCp4b1lcWovYNFEKdvat-rQw/ and Twitter feed https://twitter.com/EuropeanSociet2 2021 European Society of Medicine General Assembly Interesting info from past conferences located here https://www.slideshare.net/MOsman14 and owner LinkedIn https://www.linkedin.com/in/m-osman-5b6887206/